By Antonio Merolli, Thomas J. Joyce
This concise yet complete ebook is the 1st ebook dedicated to the purposes of biomaterials in hand surgical procedure. It offers uncomplicated wisdom within the box of biomaterials, tissue engineering, regenerative medication, implant layout, and hand joint prostheses, and explores extensive the major subject of metacarpophalangeal joint prostheses in rheumatoid sufferers. additionally, the quantity experiences the study traits for flexor tendon fix and offers new difficult principles for regeneration of peripheral nerves through synthetic nerve publications. the most objective of this paintings is to supply details in one devoted e-book that may hence symbolize a short and up to date reference for orthopedic surgeons, hand and plastic surgeons, rheumatologists, and fabrics scientists, in addition to mechanical engineers and citizens in those fields.
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6 Conclusions Extensive research activity is currently in progress worldwide to develop tissue engineering constructs for the repair of both soft and hard tissues. The combination of expertise in multidisciplinary environments will be a key factor in the development of clinical products. Biomaterials with tuned physicochemical properties will need to be made available to provide efficient encapsulation systems for cells. The use of bioactive molecules, either grafted to the scaffold or released from it in a controlled manner, seems also to be necessary to control repair of the damaged tissues.
The imposition of what are called the boundary conditions, is an extremely important part of the problem. The boundary conditions are in fact an integral part of the mathematical model that FEM solves: an erroneous choice of the boundary conditions will lead to incorrect results, irrespective of everything else. In our sample problem, we have chosen boundary conditions driven mainly by simplicity: in doing this, many important features of the problem have been disregarded: the load from the acetabular part is not a point load, but rather a distributed load, and something analogous can be said about the constraint we have applied at the prosthesis base.
Biomaterials in Hand Surgery by Antonio Merolli, Thomas J. Joyce