By James Womack
The genetic details being unlocked by way of advances in genomic and excessive throughput applied sciences is speedily revolutionizing our knowing of developmental procedures in bovine species. this data is permitting researchers remarkable perception into the genetic foundation of key features. Bovine Genomics is the 1st e-book to assemble and synthesize the knowledge discovered in the course of the bovine genome sequencing venture and consider its functional program to farm animals and dairy creation.
Bovine Genomics opens with foundational chapters at the domestication of livestock and conventional Mendelian genetics. construction on those chapters, insurance speedily strikes to quantitative genetics and the advances of entire genome applied sciences. major insurance is given to such themes as epigenetics, mapping quantitative path loci, genome-wide organization reports and genomic choice in livestock breeding. The publication is a worthy synthesis of the sector written by means of an international crew of major researchers.
Providing wide-ranging insurance of the subject, Bovine Genomic, is a necessary consultant to the sector. the elemental and utilized technology should be of use to researchers, breeders, and complicated students.
Chapter 1 The Origins of farm animals (pages 1–10): Matthew D. Teasdale and Daniel G. Bradley
Chapter 2 Mendelian Inheritance in farm animals (pages 11–19): Frank W. Nicholas
Chapter three Genetics of Coat colour in farm animals (pages 20–33): Sheila M. Schmutz
Chapter four From Quantitative Genetics to Quantitative Genomics: a private Odyssey (pages 34–50): Morris Soller
Chapter five Cartography of the Bovine Genome (pages 51–62): James E. Womack
Chapter 6 background of Linkage Mapping the Bovine Genome (pages 63–74): Stephanie D. McKay and Robert D. Schnabel
Chapter 7 Bovine X and Y Chromosomes (pages 75–100): F. Abel Ponce de Leon and Wansheng Liu
Chapter eight farm animals Comparative Genomics and Chromosomal Evolution (pages 101–108): Denis M. Larkin
Chapter nine Sequencing the Bovine Genome (pages 109–122): Kim C. Worley and Richard A. Gibbs
Chapter 10 Bovine Genome structure (pages 123–143): David L. Adelson
Chapter eleven Bovine Epigenetics and Epigenomics (pages 144–168): Xiuchun (cindy) Tian
Chapter 12 Mapping Quantitative Trait Loci (pages 169–191): Joel I. Weller
Chapter thirteen Genome?Wide organization reports and Linkage Disequilibrium in livestock (pages 192–210): M. E. Goddard and B. J. Hayes
Chapter 14 Genomic choice in red meat livestock (pages 211–233): Jeremy F. Taylor, Stephanie D. McKay, Megan M. Rolf, Holly R. Ramey, Jared E. Decker and Robert D. Schnabel
Chapter 15 effect of High?Throughput Genotyping and Sequencing at the identity of Genes and editions Underlying Phenotypic version in household livestock (pages 234–258): Michel Georges
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Additional info for Bovine Genomics
Journal of Heredity 90: 233–236. L. (2007). Genetic effects on coat colour in cattle, dilution of eumelanin and phaeomelanin pigments in an F2-Backcross Charolais×Holstein population. BMC Genetics 16: 56–67. F. (1996) Red coat color in Holstein cattle is associated with a deletion in the MSHR gene. Mammalian Genome 7: 317–318. , Howe, L. (2008) Coat-colour dilution and hypotrichosis in Hereford crossbred calves. New Zealand Veterinary Journal 56: 74–77. , Lien, S. (1995) The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination.
P1: SFK/UKS BLBS104-03 P2: SFK Womack February 27, 2012 9:41 Trim: 244mm×172mm Genetics of Coat Color in Cattle 27 However, some genes have been studied in relation to the shade of color in cattle. The silver gene or PMEL has been shown to affect the shade of coat color in some breeds. This gene has been called PMEL17 and SILV in the past. PMEL Studies have been done on the silver gene (PMEL), which is composed of 11 exons, with the coding sequence contained in exons 2–11. Some of these studies suggest that speciﬁc PMEL mutations may act as alleles involved in the dilution of one or both pigments.
The animal breeding groups (centered in Ames and Edinburgh) were focused on quantitative genetics of outcrossing populations. The plant breeding groups (centered in North Carolina and Birmingham) were focused on quantitative genetics of selfers. The two groups even used different notations for the same statistical entities. I was only made aware of the Sax paper some time later by my colleague Giora Simchen at the Hebrew University, who had received his PhD in quantitative genetics at Birmingham.
Bovine Genomics by James Womack