By Paul-Pierre Pastoret, Philip Griebel, Hervé Bazin, André Govaerts
ISBN-10: 0125464010
ISBN-13: 9780125464017
This special ebook offers a complete and comparative consultant to the immune platforms of significant vertebrate species, together with household and wild animals of veterinary or clinical curiosity, fish and amphibia. info during this crucial reference paintings has been compiled by means of world-renowned editors and a global staff of authors. for every species, the data is gifted in a established undemanding layout permitting effortless pass reference and comparability among many of the species.
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Additional info for Handbook of Vertebrate Immunology
Example text
The rearrangement of V n - D - J n segments is not a precise process with nucleotides typically removed or added before ligation of the DNA. This imprecision adds to the variability of the CDR3. This imprecise joining (called junctional diversity) occurs in Atlantic cod and rainbow trout. The overall length of CDR3 in these species is shorter than that of mammals. The length in rainbow trout peaks at 8-9 (range 4-11) amino acids and in Atlantic cod at 10 (range 8-12) compared with 10-14 (range 2-26) in human.
1972), Sigel et al. (1973), McCumber and (1972),Shankey and Clem (1976), Klapper Clem (1980a,b) and Clem (1977), Fuller et al. (1978) Morrow et al. (1983) Dogfish Scyliorhinus canicula Smooth dogfish Marchalonis and Mustelus canis Edelman (1966) Schluter et al. (1989, Gitlin et al. (1973), Sandbar shark Carcharhinus sp. 1990), Hohman et al. Rosenshein et al. (1985), (1992, 1993, 1995), Rosenshein and Bernstein et al. (1996) Marchalonis (1987), Vazquez-Moreno et aL (1992) Gitlin et al. (1973) Sigel et al.
J. Secombes, personal communication), may represent a major breakthrough in fish interleukin research. The gene is deduced to encode a polypeptide of 260 amino acids that gives a mature peptide of 150 amino acids with a predicted molecular weight of 17 kDa. Amino acid similarities of the whole molecule to mammalian ILlfls range from 49 to 55% (C. J. Secombes, personal communication). IL-2 An IL-2-1ike lymphocyte growth-promoting factor was reported in supernatants from carp leukocyte cultures stimulated by mitogen or alloantigen (Caspi and Avtalion, 1984; Grondel and Harmsen, t984).
Handbook of Vertebrate Immunology by Paul-Pierre Pastoret, Philip Griebel, Hervé Bazin, André Govaerts
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