By Alan Whiteside
ISBN-10: 0192806920
ISBN-13: 9780192806925
HIV/AIDS is definitely the worst epidemic to hit humankind because the Black dying. As of 2004 an envisioned forty million humans have been residing with the disorder, and approximately 20 million had died. regardless of quick medical advances there's nonetheless no healing and the medicine are pricey and poisonous. within the constructing global, specifically in elements of Africa, lifestyles expectancy has plummeted to under 35 years, inflicting a significant decline in monetary development, a pointy bring up in orphans, and the upcoming cave in of well-being care platforms. the inside track isn't all bleak even though. there were extraordinary breakthroughs in figuring out illnesses and constructing medicinal drugs. as the illness is so heavily associated with sexual intercourse and drug use, the necessity to comprehend and alter habit has prompted us to think again what it capability to be human and the way we must always function within the globalizing international. This Very brief creation tackles the technological know-how, the overseas and native politics, the attention-grabbing demographics, and the devastating effects of the sickness, and indicates how we needs to respond.
Reviews:
Packed with information and convenient factors of technological know-how. It won't make you a professional. yet you'll recognize what you're conversing approximately and you'll have a greater suggestion of the entire paintings we nonetheless need to do to combat this monster to the floor. Aids-free international web site. a vital read... Readers will achieve figuring out of the scientific, social, political and moral matters all in favour of this tragic epidemic. AIDSportal web site
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Additional info for HIV/AIDS: A Very Short Introduction (Very Short Introductions)
Sample text
In humans, lentiviruses result in diseases that develop over a long period, many affecting the immune system and brain. HIV has to invade cells to reproduce. Within these cells, it produces more virus particles by converting viral RNA into DNA in the cell and then making many RNA copies. The conversion is done through an enzyme called reverse transcriptase. The switch from RNA to DNA and back to RNA is significant and makes combating HIV difficult. Each time it occurs there is a possibility of errors and the virus mutating.
Eventually, the virus destroys immune cells more quickly than they can be replaced. A healthy CD4 cell count is normally over 1,000 cells per mm3 of blood. As infection progresses, this number falls, as shown in Figure 5. HIV/AIDS Stage 2 is when the count is between 350 and 499 per mm3, and symptoms might include some mild weight loss, fungal infections, and herpes zoster (shingles). When the CD4 cell count falls below 350, in stage 3, a person has advanced immunosuppression with opportunistic infections, fevers, severe weight loss, diarrhoea, candidiasis (infection with a yeast-like fungus that causes thrush), and possibly TB.
People must be exposed to the pathogen. Even then, for an infection to take hold, the immune system must be unable to resist the disease-causing organism. This is true of all infectious illnesses: we see it every year with the common cold, when most people are exposed to the virus, but some individuals manage to stave off infection while others fall sick. Thus an individual’s immune status is important in determining whether or not they are infected and how severely they are affected. Drivers of disease are mostly social and economic.
HIV/AIDS: A Very Short Introduction (Very Short Introductions) by Alan Whiteside
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