By Arief A Suriawinata MD, Swan N. Thung MD
ISBN-10: 193386494X
ISBN-13: 9781933864945
Liver Pathology: An Atlas and Concise advisor offers pathologists, hepatologists, gastroenterologists, citizens and fellows of their respective fields with an updated consultant to the differential analysis, interpretation and prognosis of liver specimens. The e-book courses the reader to appreciate universal histologic styles and key pathologic good points of the extra universal liver issues. Liver Pathology: An Atlas and Concise consultant comprises over six hundred top of the range colour pictures demonstrating the histopathologic and immunohistichemical findings supported through concise textual content together with usually linked scientific findings, pathologic beneficial properties (histology, immunohistochemistry, molecular studies), differential diagnoses, and key references. Liver Pathology: An Atlas and Concise advisor offers the "fundamentals" of liver pathology in an easy, problem-oriented presentation of key issues and ordinary differentials according to what you will definitely see. Liver Pathology: An Atlas and Concise advisor comprises concentrate on vintage beneficial properties that each pathologist is probably going to work out Differential diagnoses offered in tables for effective assessment countless numbers of top of the range photos chosen to illustrate key pathologic beneficial properties and emphasize differential prognosis chosen references and evaluation articles to guide the reader to additional research whilst wanted
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Extra info for Liver Pathology: An Atlas and Concise Guide
Example text
The nodules in nodular regenerative hyperplasia are not surrounded by fibrous septa; therefore, they are ill defined and soft, distinct from those found in cirrhosis. Irregular areas of congestion may be present, resulting in a mottled appearance of the cut surface of the liver. The nodules consist of hyperplastic hepatocytes arranged in plates more than 1-cell-layer thick, particularly adjacent or surrounding the portal tracts. 1). 2). There is little, if any, pericellular fibrosis. The hyperplastic hepatocytes are slightly larger and more variable than normal and are arranged in 2-cell-thick plates with occasional binucleation.
1 Microabscess with nuclear and cytoplasmic cytomegalovirus inclusion (arrow). 2 Coagulative necrosis in herpes simplex hepatitis (arrows). 3 Herpes simplex virus 1 immunostain shows positive staining in area of coagulative necrosis. 4 Hemorrhagic necrosis with hepatocytes containing intranuclear “blueberry-like” adenovirus inclusions (see inset) in the periphery of necrotic areas. 5 Infectious mononucleosis with atypical lymphocytes in the sinusoids. 6 Midzonal necrosis (arrows) in dengue hemorrhagic fever.
2 Normal centrilobular area demonstrating cords of hepatocytes radiating out from the terminal hepatic venule. Centrilobular hepatocytes with brown discoloration due to a normal amount of the lipofuscin pigment. Sinusoids contain red blood cells. 3 Reticulin fibers lined 1-cell-thick cords of hepatocytes in normal liver parenchyma. 4 Binucleate and polyploid hepatocytes are often found in the midzonal region at an increasing number in older individuals. 5 A small amount of macrovesicular fat droplets (in <5% of hepatocytes, arrowhead) can be encountered in an otherwise normal liver.
Liver Pathology: An Atlas and Concise Guide by Arief A Suriawinata MD, Swan N. Thung MD
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