By Robert Wyllie MD, Jeffrey S. Hyams MD, Marsha Kay MD
ISBN-10: 0323240992
ISBN-13: 9780323240994
Consult the top textual content within the box that delivers the data you must diagnose and deal with pediatric gastrointestinal and liver ailments successfully. In one handy and finished quantity, Drs. Robert Wyllie, Jeffrey S. Hyams, and Marsha Kay supply all of the most up-to-date info at the greatest new treatments, new medicines, and new suggestions in the uniqueness. additionally, the new two-color layout throughout is helping you discover what you would like quick and easily.
- Full-color endoscopy images
- Definitive advice from renowned foreign contributors who percentage their wisdom and services during this advanced box
- Detailed diagrams
- More than four hundred board review-style questions, solutions, and rationales
to aid increase your visible attractiveness
that safely illustrate complicated recommendations and supply at-a-glance acceptance of disorder procedures
to be had within the booklet integrated together with your buy
- New treatments for hepatitis B and C, new medicinal drugs for the remedy of inflammatory bowel sickness,
- The most modern info on diagnosing and treating abnormalities of protein, fats, and carbohydrate metabolism
- New chapters on pancreatic transplantation and liver pathology
- The most recent surgical options for youngsters with gastrointestinal conditions
and an extended dialogue of the most recent endoscopic and motility ideas available for pediatric sufferers
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Additional info for Pediatric Gastrointestinal and Liver Disease
Sample text
Lactoferrin, found in breast milk, is an iron-binding protein with a specific brush border receptor that increases absorption. Iron is absorbed in the proximal small intestine. Factors enhancing absorption are the Fe2+ form of iron, gastric acid, ascorbic acid, and co-ingestion with amino acids and sugars. Enterocytes not only handle iron uptake from the intestinal lumen but also exclusively regulate iron balance. 27 11 7 10 8 11-15 Copper ug/d 2 3 3 5 8 9-11 200 220 340 440 700 890 border membrane.
To easily move across this barrier, each mol ecule must be small enough, able to move down its con centration gradient, be soluble in an aqueous or lipid medium (depending on the barrier), and be charge 10 compatible. , chewing, churn ing) to generate the ample surface area required for expo sure to enzyme action. A complex network of neural and hormonal factors regulates the function of our specialized gastrointestinal cells (epithelial, muscular, and glandu lar). The digestion and absorption processes are energy consuming more so for proteins than for other sub stances; our metabolic rate increases after a meal.
66 In addition to bile acids, bile is rich in phos pholipids; both compounds are amphipathic, having both hydrophilic and lipophilic portions. The concentra tion of bile acids is usually well above a critical level where micelles (water-soluble aggregates) are formed Chapter 2 — Basic Aspects of Digestion and Absorption 17 Naϩ Bile acid 2Kϩ Naϩ, Kϩ ATPase 3Naϩ Figure 2-10. Sodium, bile acid cotransport. Figure 2-9. Fat emulsification: progressive mechanical breakdown of fat drops with addition of water-soluble coating and progressive reduction in fat droplet size.
Pediatric Gastrointestinal and Liver Disease by Robert Wyllie MD, Jeffrey S. Hyams MD, Marsha Kay MD
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