Download The Laboratory Zebrafish by Claudia Harper PDF

By Claudia Harper

ISBN-10: 1439807442

ISBN-13: 9781439807446

Like different books within the Laboratory Animal Pocket Reference Series, this advisor covers all features concerning using those organisms together with their easy biology, humane care and administration, husbandry, existence help structures, regulatory compliance, technical systems, veterinary care, and water caliber administration.

In the really short span of just a couple of many years, the zebrafish has long gone from being in most cases a pastime fish to a mainstream version animal hired through scientists to check every little thing from stem cells to the root of behavioral adjustments brought on via drug dependancy. This swift strengthen has been fueled mostly by way of a variety of and bold advances in know-how, in addition to exact characterization of the animal on a genetic and molecular point. those advancements have allowed scientists to leverage the numerous benefits of the zebrafish procedure to handle many vital questions in biology and human genetics and sickness.

However, there are few authorized and demonstrated criteria for husbandry, administration, and deal with the fish in laboratory settings or even fewer complete and consistently trustworthy assets. To this finish, the objective of this instruction manual is to supply managers, veterinarians, investigators, technicians, and regulatory team of workers with a concise but thorough reference on zebrafish biology, care, husbandry, and administration.

The goal of the publication isn't to set criteria, yet really to arm these operating with the fish with scientifically grounded ideas and primary info that may be used to layout sound fish care courses. This guide is equipped into seven chapters:

Biology
Husbandry
Life aid Systems
Management
Veterinary Care
Experimental Methodology
Resources

The ultimate bankruptcy, Resources, presents the zebrafish person with lists of resources of extra details at the zebrafish version, in addition to key references, specialist organisations, and providers of kit and offers utilized in zebrafish husbandry and care.

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Additional resources for The Laboratory Zebrafish

Example text

In vertebrates the auditory system relies on sound in the inner ear hair cells (HCs) being transduced into neural signals that are then transmitted to the brain (Tanimoto et al. 2009). The maculae, the cristae, and the organ of Corti all function to detect motion and sound (Tanimoto et al. 2009). In fish and frogs, the macular organs contain receptor hair cells and crystalline deposits of otoconia. The latter, more commonly referred to as otoliths, are important in detecting acceleration and gravity and are involved in hearing in lower vertebrates (Popper and Fay 1993; Tanimoto et al.

All fish analyzed to date, including zebrafish, possess the enzymatic apparatus for the digestion of simple and more complex carbohydrates. However, the ability to digest carbohydrates differs widely among species. To a large extent, this depends upon trophic level; herbivorous fish are typically better adapted for digesting complex carbohydrates than are carnivorous fish. 30 the laboratory zebrafish Zebrafish, as warm-water omnivores that regularly consume aquatic and terrestrial insects (and their chitinous exoskeletons) as well as phytoplankton (Spence et al.

18 the laboratory zebrafish dorsal posterior right left Dorsal Aorta anterior Internal Carotid Artery ventral Right 4th Efferent Branchial Artery Afferent Filament Artery Anterior Cardinal Vein Posterior Cardinal Vein Left 1st Afferent Branchial Artery Atrium Ductus Cuvier Rostral Vein of Ductus Cuvier Bulbus Arteriosus Sinus Venosus Hepatic Portal Vein Fat Globule Ventral Aorta Right 4th Afferent Branchial Artery Ventricle Fig. 9 An illustration of a posteroanterior view of an adult zebrafish heart and the major vasculature in the cardiac region.

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The Laboratory Zebrafish by Claudia Harper


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